of Diseases Treated by
Treatment of Incurable/Untreatable Diseases of Heart, Liver, Kidneys, by BCRO Fetal Precursor Cell Transplantation
1/ After extensive experimental work, a treatment of myocardial infarction by cell transplantation was introduced 10+ years ago by cardiologists in Paris, Dortmund, Hannover, into clinical practice.
2/ Liver cirrhosis and chronic hepatitis have been treated by fetal precursor cell transplantation with success for the last four decades.
3/ The incidence of serious kidney disease has dramatically increased lately, mostly due to autoimmunity, without any effective treatment.
It is not a common medical knowledge that the myocardial muscle cells & fibers lose their ability to proliferate after birth and their power to regenerate disappears as well. For that reason myocardial injury, as after heart attack, heals by replacement of contractile heart muscle fibers by fibrotic tissue scar, which not only cannot participate in pumping of blood, it does not contribute to passive mechanical function of the heart either.
Massive loss of cardiomyocytes after heart attack is a common cause of congestive heart failure.
Every patient after a recent heart attack with extensive (more than 70%) damage of myocardium, as determined by gallium scan upon admission to the hospital, cannot survive unless a certain substantial quantity of damaged muscle fibers (at least 50%) recovers back to normal by direct stimulation of regeneration by fetal precursor cell transplantation prepared by BCRO method so that the transplants are available immediately upon the admission to the hospital for intracoronary implantation to be carried out right after emergency stent placement into the blocked branch of coronary artery.
When the size of myocardial scar is diminished from 70% to 35% of the total myocardial mass the patient can function in life quite well and survive the second myocardial infarction with a high probability - in the rare case of survival of the massive first myocardial infarction.
Additional fetal precursor cell transplants must stimulate angiogenesis, formation of new blood vessels from the existing ones.
According to U.S. statistics 1.1 million Americans gets heart attack every year. There is 4.8. million of patients with congestive heart failure, of which over one half dies within 5 years.
All such patients should receive BCRO fetal precursor cell transplantation.
During last ten years groups of patients with recent extensive myocardial infarction incompatible with survival were treated by cell transplantation in university hospitals in Paris, France, Dortmund and Hannover, Germany, with uniformly good results. It is reported i.a. in "Handbook of Cardiovascular Cell Transplantation", published in 2004 by Martin Dunitz, a U.K. publisher.
For patients with massive heart attacks it is a matter of life or death, or a matter of debilitating disability versus ability to live reasonably well.
Cell transplants have to be implanted also into heart, although not necessarily directly into heart muscle. They can be implanted into re-opened obstructed branch of coronary artery, or into infarcted heart muscle via angiographic approach.
There are numerous German publications starting in 1950s about the non-invasive fetal precursor cell transplantation treatment of hundreds of patients with extensive myocardial infarctions, with ~72 % success rate.
Reports from Germany on treatment of over 1000 patients with decompensated congestive heart failure by fetal precursor cell transplantation show success rate from 67 to 73%.
In 1995 we treated the first 10 patients with intractable cardiac arrhythmia with nearly 100 success rate. All our patients with incurable/untreatable arrhythmias treated since then were restored to a normal cardiac rhythm.
Success rate of fetal precursor cell transplantation treatment of 150 patients with peripheral arterial disease in Germany in 1965 was 70%.
Intractable migraine, when all other treatment has failed, was treated by BCRO fetal precursor cell transplantation with success in nearly every patient,
There are many German publications starting with 1950s to confirm the value of fetal precursor cell therapy in the treatment of incurable liver diseases.
Cirrhosis of liver and chronic hepatitis were very common in Germany in 1940 - 50 - ies. This was a result of severe epidemic (actually a pandemic) of viral hepatitis in Germany during WW2 and thereafter.
Since even today there is no effective therapy for damaged liver, fetal precursor cell therapy became a treatment of choice for such serious liver diseases.
All patients with hepatitis can be helped unless their disease has advanced into the stage of portal hypertension (edema, ascites, bleeding esophageal varices, etc.).
If chronic alcoholism is the cause of liver cirrhosis, cell transplantation would be of value only if the patient would become a total abstinent.
For patients with chronic hepatitis it is mandatory to suppress an inflammatory process in the liver first, by other therapeutic means. With such approach the success of fetal precursor cell transplantation can be unexpectedly high. This applies also to chronic hepatitis C, the biggest menace of modern medicine. One cannot cure chronic hepatitis C because it is impossible to eliminate the virus causing it, but by repeated fetal precursor cell transplantation it is possible to keep viral load at low levels.
Facing the fast growing numbers of patients with severe kidney disease the nephrologists would be well advised about BCRO fetal precursor cell transplantation to be used early in the course of nephritis not responding to initial treatment. Patients usually wait before seeking help until after they already began hemodialysis and that is too late. (It is well known fact that no patient has ever improved so much after any type of stem cell transplantation to be able to stop a regular hemodialysis!)
The existing treatments of all degenerative diseases suffer from one common problem: no attempt at regeneration of degenerating cells of diseased organs and tissues is made. The sole treatment available to medicine today to directly regenerate cells, tissues and organs is BCRO fetal precursor cell transplantation.
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|Updated: December 2018|